Hospitalar Fair 2023

The Hospitalar Fair covers all sectors of health. The future of the industry is here! We are waiting to see you during May 23 to 26 in Sao Paulo.

Conox 2D launch in Italy

We encourage you to attend Conox 2D launch in Italy! The event will be held on March 9 in Verona (Green Hall – Lounge Arch) from 2 pm to 10.30 pm

Our CEO Erik Weber Jensen will give a talk about processed EEG and ICU sedation/postoperative cognitive dysfunction and delirium.

We are looking forward to seeing you there!

Arab Health 2023

Arab Health – Where the world of healthcare meets

We are happy to announce that we will be presenting our products at Arab Health Exhibition in Dubai from 30/1/2023 until 2/2/2023.

Medica 2022 – Leading International Trade Fair

Medica is the the best meeting point for specialists, investors, agents, distributors and professionals from more than 170 countries. The World Forum for Medicine takes place 14-17 November in Düsseldorf, Germany.

We are happy to announce that we are part of MEDICA 2022.Quantium Medical will be located in Hall 11 Stand 11G02.

We encourage you to attend and book a meeting with us.

More information here

Curso TIVA y Neurociencias BCN 2022

The first course on pharmacology applied to perfusions and neurosciences in Anesthesia will be held on June 17 and 18.

The course will take place at Parc Santiari Sant Joan de Déu (Barcelona) with both national and international professors. Among them will be Erik Weber Jensen (CEO of Quantium Medical).

We encourage you to register if you are interested in these topics! If you have any questions, please contact tivayneurociencias@gmail.com

Monitoring the brain during anaesthesia in 2021

Monitoring the Brain during Anaesthesia in 2021

Join us on Saturday, October 23rd to learn more about “Monitoring the nociception / antinociception balance during general anaesthesia” with Dr. Erik Weber Jensen. ¡Do not miss the opportunity to register!

Register today!

Lives Digital 2020

European Society of Intensive Care Medicine – ESICM 2020

33rd Annual Congress – DIGITAL

This year due to the Covid-19 , ESICM has decided to transition the congress to an online event stimulating face-to-face meeting. The congress dates willbe 06-09 December 2020.

Visit the Fresenius Kabi virtual booth and learn more about providing Healthcare Professionals with Integrated and Innovative Solutions.

Click here to enter


Save the date

Effects of Depth of Anesthesia Monitored by IoC on Patients Undergoing Laparoscopic Radical Resection of Colorectal Cancer

The monitor and IoC parameters indicated in this article are fully based on Quantium’s qCON and qNOX imbedded OEM technology, ideal for Laparoscopic and any other surgery requiring a patient to be fully aenesthetized.

In this article by Jie Zhao, Zhenming Kang, Wenqin Xie, Huimei Lin, and Yang Liu published in Molecular Therapy, 18 September 2020 you can read more about Index of consciousness IoC1 (qCon) and IoC2 (qNox) and Effects of depth of Anesthesia.

Laparoscopic radical resection has been widely used for the treatment of colorectal cancer since the 1980s. Adjusting the precise anesthetic dosage has been confirmed to enhance patient recovery and also mitigate complications related to anaesthesia.

Check out if you want to read the complete article.

anesthesia

World Anaesthesia Day

William T.G Morton

Every now and then there are men and women who discover or achieve something extraordinary that ultimately helps mankind in one way or another.

“A small step for men, a great step for mankind”, famous words from the astronaut Neil Armstrong when he placed the first footstep on the moon surface on July 20th 1969.

Something similar must have gone through the head of William T. G. Morton (1819-1868) when he made history while preforming the first public and successful demonstration of anaesthesia for surgical purposes. Imagining the surgical procedures that were performed before the 19th century will probably shock more than one, as many deaths occurred during surgery before anaesthesia was discovered.

This discovery helped medicine make a huge leap forward by finally providing the means to eliminate (or at least reduce drastically) the suffering associated with surgical interventions.

Today, 174 years later we are celebrating the first public and successful demonstration of anaesthesia for surgical purposes. William Morton is certainly one of those forgotten heroes of history, to whom Quantium Medical would like to pay homage on this special day.

He would probably boast a great smile if he knew how many millions of surgeries are safely taking place everyday thanks to his efforts and the hard work of the Anaesthesiologists who master this discipline.

REG

Continuous improvement at Quantium Medical

The solutions provided by Quantium Medical are widely used either as OEM for integration by monitor manufacturers, or as finished products created by the company.

With install bases in Europe, Asia, Latin America, and Middle East, we are proud of our global footprint.

Nonetheless, it’s not just about offering a proven solution! We live in an evolving world and technology needs to keep improving thanks to customer feedback, constant research, and a solid R&D team.

The success of our qCON / qNOX and Conox solutions is based on constant research through collaboration projects with different hospitals in Europe, US and Asia.

We are constantly reviewing our specs and looking to improve not only how our technology works, but also looking into how we can add more value to patient monitoring.

Recently one of our lead R&D persons (Carmen González Pijuan, PhD in Biomedical Engineering) concluded successfully a 3-year research project, allowing us to take our monitoring solutions to a next level.

Following is a summary of this research, for which Quantium medical has already filed a patent application: PCT/EP2018/064061.

Depth of anaesthesia monitoring integrating cerebral blood flow estimations

Cerebral blood flow (CBF) reflects the rate of delivery of arterial blood to the brain. Since no nutrients, oxygen or water can be stored in the cranial cavity due to space and pressure restrictions, a continuous perfusion of the brain is critical for survival. Anaesthetic procedures are known to affect cerebral haemodynamics, but CBF is only monitored in critical patients due, among others, to the lack of continuous and easy to use bedside monitors for this purpose.

Our research proposes a potential solution through bioelectrical impedance technology, also known as rheoencephalography (REG). The underlying hypothesis is that REG signals carry information on CBF that might be recovered by means of the application of advanced signal processing techniques, allowing us to track CBF alterations during anaesthetic procedures. 

The strength of Quantium Medical is its capacity to provide new indices by applying advanced mathematical models. Throughout this research a series of analysis techniques and monitoring solutions have been used to create a solid baseline analysis that has provided valuable conclusions.

The relationship between global haemodynamics, cerebral haemodynamics and EEG based parameters are analysed, looking for causal relationships among them. Interactions were detected during anaesthetic drug infusion and patient positioning, providing evidence of the coupling between haemodynamics and brain activity.

As mentioned, causal interactions between general haemodynamics, cerebral haemodynamics and brain activity have been studied. A first analysis along complete surgical procedures has been performed, followed by a breakdown of specific events such as patient positioning or drug infusion. Brain activity, represented by EEG related variables, showed a causal relationship with haemodynamics, suggesting that clinical decisions related to anaesthesia should integrate CBF measurements to preserve hemodynamic stability at a general and cerebral level.

During propofol general anaesthesia, both CBF and EEG signals suffer changes due to the induced loss of consciousness and depressed hemodynamic activity. Our research was aimed at analysing the causal relationships between both physiological signals during anaesthetic procedures.

Besides the direct effects of propofol concentration changes in all the physiological variables under study, the causal relationships among haemodynamics and EEG might also be affected by the administration of the hypnotic drug. Even though the detected interactions are similar to those during steady state anaesthesia, several differences can be appreciated. For instance, the occurrence of causal interactions from HR and MAP towards CBF PP, CBF lin and EEG are higher, suggesting that changes in HR caused by propofol are projected in CBF and EEG. Additionally, causal effects from CBF linked to HR and EEG are also more frequent under propofol infusion, while the interactions between MAP and HR have a lower occurrence. Overall, changing the propofol effect site concentration elicits a higher number of interactions from both cerebral and global haemodynamics towards EEG.

Figure 1: Sensor electrodes positioning on forehead for accurate REG measurement.

Conclusions

The causal relationships between REG signals and other physiological data were assessed to explore the adequacy and need for REG monitoring during surgery. Overall, considering all the surgical procedures, interactions between general haemodynamics, brain haemodynamics and electroencephalographic activity (EEG) were detected, confirming the hypothesis that CBF is linked to both the hemodynamic stability and the brain activity modulated by anaesthetic drugs. Additionally, specific events during the anaesthetic procedures were analysed as well, such as drug infusion, patient positioning and the administration of vasoactive drugs. In all those cases, causal interactions were detected, showing that decisions on drug dosages and patient positioning should be made considering both the hemodynamic stability and depth of anaesthesia simultaneously, since hemodynamic changes might induce brain activity levels to increase or decrease, and vice versa.

From a scientific perspective, the results of this research project justify a new opportunity for REG signals, since the application of advanced signal processing techniques has shown to be effective in tracking CBF information embedded in REG recordings. Moreover, the interaction among different physiological networks has been further assessed and quantified, contributing to the knowledge on the effects of anaesthetics in the brain and the mechanisms cooperating to achieve a successful and stable anaesthetic state. Considering the clinical benefits, CBF monitoring through REG could be extended to all kind of patients, even to those initially at low risk, making it possible to reduce the occurrence of adverse events that might sometimes have deleterious effects for patients.

Contact us if you want to know more